Dr. Ryan A Harris

 
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  Ryan A Harris, PhD, CEP, FACSM 

FACULTY, GEORGIA PREVENTION INSTITUTE
 Professor Medicine, Pediatrics, Physiology & Graduate Studies
Associate Director, Georgia Prevention Institue
Director, Laboratory of Integrative Vascular and Exercise Physiology ()
Director, Human Physiology Core

Contact Information

Link to CV

Dr. Harris's present research interests involve the interaction among oxidative stress, inflammation and endothelial dysfunction as they relate to cardiovascular disease. He is interested in the endothelium, a mono-layer of cells that lines all the blood vessels. Specifically, Flow-mediated dilation (FMD), a functional non-invasive bio-assay of endothelial function (a manifestation of cardiovascular disease) is measured in conjunction with various inflammatory and oxidative stress biomarkers in response to different systemic perturbations (i.e. exercise, high-fat meal, oral antioxidants, oral BH4, etc). Endothelial dysfunction is observed in many clinical populations. Over the next several years, he plans to pursue research questions: 1) identifying the mechanisms of oxidative stress in various clinical populations (i.e., COPD, Obesity, and Diabetes), 2) investigating the cardio-protective role of estrogen following various perturbations (i.e. exercise, high-fat meal, antioxidant therapy, etc.), and 3) identifying an acceptable methodology of the traditional FMD test that will ultimately be embraced clinically.

Education

Postdoctoral Training
University of California, San Diego, California 2007-2009
Interventional Vascular Physiology

PhD
Indiana University, Bloomington, Indiana 2007
Clinical Exercise Physiology

MS
California State University Hayward, California 2002
Exercise Physiology

BS 
San Diego State University, San Diego, California 1999
Kinesiology; Fitness, Nutrition and Health

Certification
American College of Sports Medicine
Certified Clinical Exercise Physiologist (CEP)

Projects

鈥淲hole Body Vibration in Knee Osteoarthritis鈥�

Industry Sponsored  (Harris, PI)                                            
July 2024 through June 2026
Role: Principal Investigator

鈥淕eorgia Cystic Fibrosis Research and Translation Core Center鈥�

2P30DK125013  
National Institutes of Health (Harris, PI)                                            
September 2023 through June 2028
Role: Multi-Principal Investigator

The major goal of this project is to develop and integrate the electronic medical record data with the research data for people with CF across the state of Georgia.

鈥淗ealth Disparities and Vascular Aging Over Time in New Onset Cancer鈥�

American Heart Association SFRN (Harris, PI PRoject 2)                                                                  
July 2021 through June 2026
Role: Principal Investigator

The major goal of project 2 of the SFRN is to understand the role of health disparities in vascular aging over time in new onset breast and prostate cancer.

Honors & Awards

2017 
Exemplary Teaching Award, 星空传媒

2015 
Exemplary Teaching Award, 星空传媒

2014
Outstanding Young Basic Science Faculty Award, 星空传媒

2014
Emerging Scientist Award, 星空传媒 Research Institute

2012
Achieved Fellowship for the American College of Sports Medicine (ACSM)

2011
Clinical Science Young Investigator Award, American Physiological Society, CV section

2011
Outstanding Young Clinical Science Faculty Award, Georgia Health Sciences University

2010
National Institutes of Health, Loan Repayment Program Award

Select Publications

  1. Crain, B., C. Harris, M.P. Bellissimo, E.A. Ivie, W.R. Hunt, V. Tangpricha, T.R. Ziegler, A. Harris, J. Alvarez. Interrelationships Between Handgrip Strength, Body Composition, Physical Activity, and Quality of Life in Adults with Cystic Fibrosis. Nutrition in Clinical Practice. In Press.
  2. Joseph, S., A. Bhadwaj, J Skariah, I Aggarwal, V. Shah, A. Harris. Effects of education level on natural language processing in cardiovascular health communication. Frontiers in Public Health, Digital Public Health.  In Press.
  3. Simon, A.B., D. Trivedi, J. Thomas, M.S. Nicholson, A. Harris. Sex specific associations of prolactin and progesterone with glycemic control in adults with type 1 diabetes. Clinical Medicine Insights: Endocrinology and Diabetes. In Press.
  4. Pollard, E., A. Guha, A. Harris, X. Wang, H. Zhu, Y. Dong, N.L. Weintraub, M.H. Tsai. Cancer history and cardiovascular disease: Implications for colorectal and breast cancer screening. Journal of Medical Screening. In Press.
  5. Gonzalez-Ramirez, L.A., P. Suppakitjanusant, T.M. Burley, S. Zaveri, A.A. Stecenko, W.R. Hunt, A. Harris, V.A. Stallings, E.A Ivie, C. Driggers, J.N. Binongo, T.R. Ziegler, J.A Alvarez.  Relationship between skeletal muscle indicators and clinical outcomes in cystic fibrosis is modified by adiposity and CFTR modulator use: A cross-sectional analysis.  The American Journal of Clinical Nutrition. In Press.
  6. Broniec, M.N., K. Norland, J. Looney, R. Crandall, J. Thomas, X.Wang, A. Harris. Increased skeletal muscle oxidative capacity augments the myokine response to whole body vibration. Medicine and Science in Sports and Exercise. In Press.
  7. Nain, P., O.M. Makram, V. Shah, H.H. Kunhiraman, N. Stabellini, B. Datta, S. Jiang, V. Patel, L. Seth, A. Bhave, S.A. Malick, Y. Gong, M.G. Fradley, D. Leong, A. Harris, Y. Hung, A. Lin, N.L. Weintraub, A. Guha. Impact of diabetes and metformin on cardiovascular outcomes in prostate cancer patients aged 66 and older: Role of social determinants of health and racial disparities. Cancers. In Press.
  8. Alotaibi, N.Z., D.H Lein, H.K. Yuen, A. Harris, S. Krick, E.P. Plaisance, J. Lowman. Survey Validation of Exercise and Body Composition Testing and Exercise Training Programs for People with Cystic Fibrosis: A Delphi Study.  Pediatric Pulmonology. In Press
  9. Simon, AB, J.C. Looney, M. Blackburn, R. Crandall, J. Thomas, P. Kellam, M. Mullen, A. Guha, P. Raval, N.L. Weintraub, A Harris. Racial disparity in microvascular function among women with newly diagnosed breast cancer. American Journal of Physiology 鈥� Heart and Circulatory Physiology. In Press.
  10. Tessier, E.A.S, C. Daltro, E.M. Netto, G.M. de Aragao Doria, A.J Gutierrez Peredo, F. Bulhoes, R. Aras, A. Harris. Endothelial function by flow-mediated dilation (FMD) in the brachial artery in hypertensive patients. Arq Bras Cardiol. 2025, 122(5): e20240533.
  11. Simon AB, C.J. Weeks, A. Harris, S.S. Athni. The Impact of Metabolic Control on Limb Differences in Peripheral Neuropathy: A Pilot Study. Journal of Neurology Research. 2025. 15(2): 71-76.
  12. Allan, J.M., B.M. Fox, M. Kasztan, G.C. Kelly, P.A. Molina, M.A. King, J. Colson, L. Wells, L. Bowman, M. Blackburn, A. Kutlar, A. Harris, D.M. Pollock, J.S. Pollock. Enhanced Vasoconstriction in Sickle Cell Disease is Dependent on ETA Receptor Activation.  Clinical Science, 138(23):1505-1520, 2024.
  13. Anh, W., F.N. Burnett, K.Wojnar-Lason, J. Doja, A. Sreekumar, P. Ghoshal, B. Singla, G. Gonsalvez, A. Harris, X. Wang, J. Miano, G. Csyani. Activation of receptor-independent fluid-phase pinocytosis promotes foamy monocyte formation in atherosclerotic mice. Redox Biology, 2024, 103423, ISSN 2213-2317, .
  14. Guha, A., O.M. Makram, P.Nain, N.Stabellini, B.Datta, S.Jiang, V.Patel, L.Seth, A.Bhave, S.A. Malik, Y. Gong, M.G Fradley, D. Leong, A. Harris, N.L. Weintraub. Disparities in diabetes-related outcomes in prostate cancer patients-role of social determinants of health and race, European Heart Journal, Volume 45, Issue Supplement_1, October 2024, ehae666.3155. .
  15. Simon AB, Bajaj P, Samson J, Harris RA. The Clinical Utility of Whole Body Vibration: A Review of the Different Types and Dosing for Application in Metabolic Diseases. Journal of Clinical Medicine. 2024; 13(17):5249. *Corresponding Author
  16. Broniec, M, K. Norland, J. Thomas, X. Wang, A. Harris. The decorin and myostatin response to acute whole body vibration: Impact of Adiposity, Sex, and Race. International Journal of Obesity, 2024 *Corresponding Author
  17. Malik, S., Guha, X. Wang,  N.L. Weintraub, R.A. Harris, B. Datta, J. Moore, P. Nain, S. Patel, S. Coughlin, E. Polter, A.E. Prizment, A Blaes, R. Florido, S. Kutty, A. Alonso, C. Joshu, E. Platz.  Association between Obesity and Risk of Total and Obesity-Related Cancer in Persons with Incident Cardiovascular Disease. Journal of American Heart Association. 2024 13(17)
  18. Simon, A.B., C.C Derella, J. Looney, K. Norland, X. Wang, A. Harris. Daily physical activity does not contribute to differences in muscle oxidative capacity between overweight and obesity. Endocrinology, Diabetes & Metabolism. 7(15): e513, 2024 . *Corresponding Author
  19. Nain, P. N. Stabellini, S Yerraguntla, G. Gopu, A. Bhave, L. Seth, V. Patel, S. Jiang, S. Malik, N.L. Weintraub, A.J. Montero, A. Fofanah, J. Cullen, N. Agarwal. X. Wang, B. Ky, L.A. Baldassarre, A. Harris, A. Guha. Adverse social determinants of health elevate uncontrolled hypertension risk: A cardio-oncology prospective cohort study. JNCI Cancer Spectrum. 8(5): 2024 .
  20. M. Makram, H.H Kunhiraman, R.A. Harris, C.C. Hedrick, K. Nasir, N.L. Weintraub, X. Wang, A. Guha. Examining the interplay between cardiovascular disease and cancer incidence: Data from NHANES III and continuous. American Heart Journal Plus: Cardiology Research and Practice, Volume 40, 100380, 2024.
  21. Ahn, W, F.N. Burnett, A. Pandey, P. Ghoshal, B. Singla, A.B. Simon, C.C. Derella, A. Harris, R. Lucas, G. Csanyi. SARS-CoV-2 spike protein stimulates micropinocytosis in murine and human macrophages via PKC-NADPH oxidase signaling.  Antioxidants. 13(2): 175, 2024 
  22. Massengale, K., V. Barnes, C. Williams, A. Mansuri, K. Norland, M. Altvater, H. Bailey, A. Harris, S. Su, W. Wang. Nocturnal BP dipping, BP variability and cognitive function in early and middle-aged adults.  The Journal of Clinical Hypertension.  26(3): 235-240, 2024.
 


CONTACT DR. RYAN A HARRIS

  Campus (HS, 1707)
  1120 15th Street, 星空传媒, GA 30912
  706-721-5998       706-721-7150
  ryharris@augusta.edu